Depends. I have two arrangements I prefer:
1: Fusca built to do damage, rufa mortars that boost physical damage, and taunt majors that provide damage reduction and resist 3 damage per hit. All of the ants support one another, and are built to operate as a collective.
2: Fusca built to take damage, rufa rapid-fire that utilize and boost venom damage, and stun majors that provide recoil and can take a maximum of 20 damage per hit.